The world we want to live in With U-Factor® solution, we aim to create A world free ofintractable diseases

Amyotrophic Lateral Sclerosis (ALS) is a disease characterized by the progressive weakening and wasting of muscles in the hands, feet, throat, tongue, and those necessary for breathing, leading to a gradual loss of these functions. In Japan, the number of patients is estimated to be around 10,000, with 1,000 to 2,000 new diagnoses each year. It is one of the representative intractable diseases for which there is currently no effective treatment.

Glaucoma is a condition where abnormalities in the visual field occur, gradually narrowing the area of vision. In Japan, the number of patients is estimated to be approximately 64,900, with a prevalence rate of 5% among those aged 40 and over, meaning about 1 in 20 people.

Dry Eye: It is a condition where tears are unable to consistently protect the surface of the eye, leading to dryness and visual disturbances. In Japan, it is estimated to affect over 22 million people, making it a widespread issue.

When a blood vessel in the brain becomes blocked, it restricts blood flow, resulting in damage to brain tissue. This can lead to functional impairments such as hemiplegia (motor paralysis), speech disorders, and swallowing difficulties.

Alzheimer's disease is a progressive neurodegenerative disorder characterized by the abnormal accumulation of amyloid-beta and tau proteins in the brain, leading to the gradual loss of neurons. This results in cognitive impairments such as memory loss, disorientation, and decreased judgment, which progressively worsen and interfere with daily life. The risk of developing the disease increases with age, and there is currently no established cure.

A cerebral aneurysm is a condition where a part of a blood vessel in the brain balloons out, causing the vessel wall to thin and increasing the risk of rupture. If it ruptures, it can lead to intracerebral hemorrhage or subarachnoid hemorrhage. This can result in sudden severe headaches, loss of consciousness, paralysis, and other neurological symptoms. Without appropriate treatment, it can lead to life-threatening situations or severe long-term complications.

*Number of Patients with Cerebrovascular Disease

Muscular dystrophy is a group of genetic disorders characterized by progressive muscle weakness and atrophy due to defects in the production of proteins needed to form healthy muscle. Symptoms include difficulty walking, decreased respiratory function, and cardiac issues. The age of onset and rate of progression vary depending on the type of muscular dystrophy. It is classified into several types, including Duchenne and Becker muscular dystrophies.

Crohn's disease is an intractable condition characterized by chronic inflammation of the digestive tract, primarily affecting the small intestine and colon. It is marked by symptoms such as abdominal pain, diarrhea, and weight loss. The inflammation can penetrate the intestinal wall, leading to the formation of fistulas and causing strictures. Although the exact cause is unknown, it is believed to involve genetic factors and environmental influences.

Parkinson's disease is a progressive neurodegenerative disorder characterized by the gradual loss of dopamine-producing neurons in the substantia nigra region of the brain. It is marked by motor symptoms such as tremors in the hands and feet, muscle rigidity, bradykinesia (slowness of movement), and postural instability. Non-motor symptoms can include sleep disturbances, depression, and other psychiatric issues. While there is no cure for Parkinson's disease, treatment primarily consists of medication to alleviate symptoms and improve the patient's quality of life.